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    Area of Science:

    • Public Health
    • Epidemiology
    • Biostatistics

    Background:

    • Mortality statistics are crucial for understanding population health trends.
    • Identifying leading causes of death informs public health interventions and resource allocation.
    • Previous reports provide historical context for U.S. mortality data.

    Purpose of the Study:

    • To present final 2017 U.S. mortality data for the 10 leading causes of death.
    • To analyze these causes by age, sex, race, and Hispanic origin.
    • To detail leading causes of infant, neonatal, and postneonatal mortality.

    Main Methods:

    • Utilized final 2017 death certificate data from all 50 states and D.C.
    • Classified causes of death using the International Classification of Diseases, 10th Revision (ICD-10).
    • Ranked causes based on the number of deaths attributed to the underlying cause.

    Main Results:

    • The 10 leading causes accounted for 74% of all U.S. deaths in 2017.
    • Top causes included heart disease, malignant neoplasms, and unintentional injuries.
    • Significant variations in leading causes were observed across different demographic groups.
    • Leading infant causes were congenital malformations, short gestation/low birth weight, and maternal complications.

    Conclusions:

    • Heart disease and cancer remain the primary drivers of mortality in the U.S.
    • Understanding demographic variations in causes of death is essential for targeted public health strategies.
    • Specific factors dominate infant mortality, necessitating focused research and prevention efforts.