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NTD Diagnostics for Disease Elimination: A Review
1Department of Social Anthropology, University of Edinburgh, Edinburgh EH8 9LD, UK.
Diagnostics (Basel, Switzerland)
|June 11, 2020
Summary
Achieving disease elimination for Neglected Tropical Diseases (NTDs) requires tailored diagnostic strategies. Current diagnostic tools and development pipelines need enhancement to meet the demands of NTD elimination goals.
Area of Science:
- Global Health
- Infectious Diseases
- Diagnostic Technologies
Background:
- Neglected Tropical Diseases (NTDs) elimination goals necessitate a shift from generalized interventions to locally adapted strategies.
- Diagnosis plays a crucial role in adapting NTD elimination programs to specific local contexts and informing programmatic decisions.
Purpose of the Study:
- To explore debates surrounding diagnostic technologies for NTD elimination.
- To identify the roles and ideal characteristics of diagnostic tests for NTDs.
- To summarize the current state of diagnosis for three NTDs with elimination targets.
Main Methods:
- A scoping review was conducted to analyze literature on diagnostic approaches for NTD elimination.
- Emphasis was placed on point-of-care testing relevant to remote and underserved regions where NTDs are prevalent.
Main Results:
- NTD elimination goals redefine the purpose and applications of diagnostic tools.
- Current diagnostic capabilities and development pipelines are insufficient for many NTDs.
- Point-of-care testing is critical for NTD control in resource-limited settings.
Conclusions:
- Tailored diagnostic strategies are essential for successful NTD elimination.
- A framework is needed to guide research and investment in NTD diagnostics.
- Addressing deficiencies in the diagnostic pipeline is crucial for achieving global health goals.
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