Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

711
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
711
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

343
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
343
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

647
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
647
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

388
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
388
Renal Corpuscle01:20

Renal Corpuscle

6.5K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
6.5K
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

200
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
200

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Primary Vesicoureteral Reflux and Renal Scarring.

Pediatric clinics of North America·2023
Same author

Treatment of BK virus with a stepwise immunosuppression reduction and intravenous immunoglobulin in pediatric kidney transplant.

Pediatric transplantation·2022
Same author

Kidney Echogenicity and Vesicoureteral Reflux in Children with Febrile Urinary Tract Infection.

The Journal of pediatrics·2021
Same author

Clinical profile of children incidentally found to have advanced kidney failure.

Pediatric nephrology (Berlin, Germany)·2021
Same author

Acute Kidney Injury in Pediatric Acute SARS-CoV-2 Infection and Multisystem Inflammatory Syndrome in Children (MIS-C): Is There a Difference?

Frontiers in pediatrics·2021
Same author

A 6-year-old male with acute kidney injury and enlarged kidneys: Questions.

Pediatric nephrology (Berlin, Germany)·2020
Same journal

Centering Lived Experience: Inclusive Pediatric Care for Children Who Are Deaf and Hard of Hearing and Their Families.

Pediatric annals·2026
Same journal

From Early Childhood to Adulthood: Implementing Neuroaffirming Health Care for Autistic Individuals.

Pediatric annals·2026
Same journal

Neurodivergence in Medical Education: Current Landscape and Inclusive Future for Pediatrics.

Pediatric annals·2026
Same journal

Neurodiversity and Intellectual Disability: Opportunities and Challenges for Functioning and Participation Across the Life Course.

Pediatric annals·2026
Same journal

Action for Access: Equity for Children With Disabilities in Lowand Middle-Income Countries.

Pediatric annals·2026
Same journal

Rethinking "Healthy" for Every Child: Building Flexible, Family Centered Routines in a Neurodiverse World.

Pediatric annals·2026
See all related articles

Related Experiment Video

Updated: Dec 18, 2025

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

3.0K

Postinfectious Glomerulonephritis.

Dunya Mohammad, Rossana Baracco

    Pediatric Annals
    |June 11, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Postinfectious glomerulonephritis is a common childhood kidney disease. Most children recover fully with no recurrence, despite various pathogen triggers.

    More Related Videos

    Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
    09:43

    Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

    Published on: June 8, 2022

    3.4K
    Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins
    09:12

    Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins

    Published on: January 18, 2019

    9.8K

    Related Experiment Videos

    Last Updated: Dec 18, 2025

    Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
    10:33

    Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

    Published on: December 17, 2021

    3.0K
    Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
    09:43

    Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

    Published on: June 8, 2022

    3.4K
    Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins
    09:12

    Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins

    Published on: January 18, 2019

    9.8K

    Area of Science:

    • Pediatric Nephrology
    • Immunology

    Background:

    • Postinfectious glomerulonephritis (PIGN) is the leading cause of acute glomerulonephritis in children.
    • Historically linked to streptococcal infections, PIGN is now recognized to be triggered by diverse pathogens.
    • Pathogen-induced immune responses can lead to glomerular injury.

    Purpose of the Study:

    • To summarize the epidemiology, clinical presentation, diagnostic evaluation, and management strategies for PIGN in pediatric patients.
    • To provide an overview of the current understanding of PIGN in children.

    Main Methods:

    • Review of existing literature on postinfectious glomerulonephritis in children.
    • Synthesis of information regarding history, presentation, evaluation, differential diagnosis, and management.
    • Focus on clinical outcomes and prognosis.

    Main Results:

    • Postinfectious glomerulonephritis is the most frequent cause of acute glomerulonephritis in pediatric populations.
    • A wide range of infectious agents, beyond Streptococcus, can initiate the condition.
    • The majority of affected children experience complete recovery of kidney function without relapse.

    Conclusions:

    • Postinfectious glomerulonephritis in children generally carries an excellent prognosis.
    • Prompt evaluation and appropriate management are key to ensuring favorable outcomes.
    • Understanding the diverse etiologies is crucial for accurate diagnosis and treatment.