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Updated: Dec 18, 2025

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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
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Uncommonly sited rare tumour causing nasal obstruction
Christina Apthorp1,2, Shweta Sharma3, H Barrak Aldeerawi3
1ENT, South Warwickshire General Hospitals NHS Trust, Warwick, UK christina@apthorp.me.uk.
BMJ Case Reports
|June 12, 2020
Summary
This study reports a rare case of nasal angioleiomyoma, a benign tumor causing nasal obstruction. Early diagnosis and surgical resection are key for effective management of this uncommon condition.
Area of Science:
- Otolaryngology
- Surgical Pathology
Background:
- Angioleiomyomas are rare benign tumors typically found in the lower extremities.
- Nasal angioleiomyomas are exceptionally uncommon, presenting diagnostic challenges due to their unusual location.
Observation:
- A 64-year-old woman presented with unilateral nasal obstruction due to a 1 cm cystic lesion on the lateral wall of the right nasal cavity.
- The lesion, located at the mucocutaneous junction, was firm, broad-based, and not attached to underlying cartilage.
Findings:
- Endoscopic examination confirmed the lesion's localized nature without further nasal cavity extension.
- Surgical resection was successfully performed using an endonasal approach.
Implications:
- This case underscores the importance of including angioleiomyomas in the differential diagnosis for nasal obstruction, even in rare locations.
- Highlights the need for thorough evaluation of nasal masses to ensure accurate diagnosis and appropriate treatment.
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