[ENDOMETRIOSIS AND PREGNANCY (REVIEW)]

Area of Science:

• Reproductive Medicine
• Gynecology
• Obstetrics

Background:

• Endometriosis presents complex challenges for fertility and pregnancy management.
• Pathogenesis involves anatomical, hormonal, and peritoneal factors impacting oocyte and endometrial health.
• Existing data on pregnancy's effect on endometriosis are contradictory.

Purpose of the Study:

• To review and systematize current data on endometriosis's impact on fertility.
• To analyze endometriosis's effects on pregnancy course and outcomes.
• To explore the diagnosis of endometriotic implant changes during pregnancy.

Main Methods:

• Systematic review of existing literature.
• Analysis of factors affecting fertility in endometriosis patients.
• Evaluation of pregnancy outcomes in women with endometriosis.

Main Results:

• Endometriosis contributes to infertility through various mechanisms, including anatomical distortions and impaired folliculogenesis.
• Pregnancy may positively influence endometriosis symptoms and implant size, but outcomes are inconsistent.
• Endometriosis can negatively affect pregnancy outcomes, with unpredictable changes in endometriotic implants.

Conclusions:

• Further understanding of endometriosis pathogenesis is crucial for informed obstetric decisions and preventing iatrogenic complications.
• Patients with endometriosis require comprehensive counseling regarding pregnancy risks and management.
• Predicting changes in endometriotic implants during pregnancy requires more research.