Related Experiment Video

Updated: Dec 18, 2025

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
08:45

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients

Published on: April 18, 2025

939

[INDICATORS OF SYSTEMIC INFLAMMATORY RESPONSE AMONG PATIENTS WITH URGENCY HYPERTENSIVE CRISES]

B Goldovsky1, D Leliuk1, K Otarashvili1

  • 1State Institute «Zaporizhzhia Medical Academy of Postgraduate Education of Ministry of Health of Ukraine».

Georgian Medical News
|June 15, 2020
PubMed

Insights

Hypertensive crises show increased inflammatory markers like IL-6 and TNF-б, linked to higher blood pressure. This suggests inflammation plays a key role in managing hypertension emergencies.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Emergency Medicine

Background:

  • Uncomplicated hypertensive crises require optimized prehospital treatment.
  • Understanding systemic hemodynamics and autonomic nervous system balance is crucial.

Purpose of the Study:

  • To improve prehospital treatment of hypertensive crises.
  • To investigate systemic hemodynamics, autonomic nervous system balance, and inflammatory markers in hypertensive patients.

Main Methods:

  • Prospective, comparative study of 206 patients with stage II hypertension.
  • Analysis of systemic inflammatory response markers (e.g., IL-6, TNF-б, CRP, IL-1в).
  • Comparison between emergency medical services patients, outpatients, and healthy individuals.

Main Results:

  • Increased serum proinflammatory markers correlate with elevated blood pressure.
  • Elevated catecholamines are associated with increased levels of IL-6 and TNF-б.
  • C-reactive protein (CRP) may indicate vascular inflammation; IL-1в is an early inflammatory response factor.

Conclusions:

  • Inflammatory processes are significantly involved in uncomplicated hypertensive crises.
  • Systemic inflammation markers offer insights into managing hypertensive emergencies.
  • Further research into inflammatory pathways could refine prehospital hypertension treatment.

More Related Videos

Author Spotlight: Developing Innovative Therapeutic Strategies for Hemorrhagic Shock Research08:14

Author Spotlight: Developing Innovative Therapeutic Strategies for Hemorrhagic Shock Research

Published on: March 22, 2024

1.9K
Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis04:05

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

Published on: June 30, 2023

2.6K

Related Concept Videos

Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
556
Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
1.0K
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
358
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
425
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
134
Inflammatory Response I: Vascular and Cellular01:30

Inflammatory Response I: Vascular and Cellular

The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
15.4K