Related Experiment Video
Updated: Dec 18, 2025

15:29
Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
Published on: August 5, 2016
8.5K
Brucellosis: An Elusive Backyard Agent
Zain Rizvi1, Tahir Iqbal1, Haider Bokhary2
1Internal Medicine, Shifa International Hospital, Islamabad, PAK.
Cureus
|June 19, 2020
Summary
Brucellosis, a zoonotic infection, often presents as prolonged fever of unknown origin. This case highlights its diagnosis in a man with persistent pyrexia, confirmed by positive antibody titers.
Area of Science:
- Infectious Diseases
- Zoonotic Infections
- Microbiology
Background:
- Brucellosis is a zoonotic infection caused by Brucella species.
- Commonly presents as pyrexia of unknown origin with systemic symptoms like night sweats, malaise, arthralgias, and myalgias.
- Differential diagnosis for prolonged fever is crucial, especially when considering exposure to contaminated food products.
Observation:
- This report details a case of a male patient presenting with a month-long history of PUO.
- Enteric fever was excluded, and brucellosis was considered due to clinical suspicion and potential exposure to contaminated food products.
Findings:
- Blood tests confirmed brucellosis by revealing positive antibody titers.
- The diagnosis was linked to suspected exposure from inadequate sterilization of food products, indicating a systemic infection.
Implications:
- This case underscores the diagnostic challenge of brucellosis presenting as PUO.
- It emphasizes the need for thorough investigation, including serological testing, in endemic areas or with suspected foodborne zoonotic exposure.
- Highlights public health concerns regarding food safety and sterilization practices.
Related Concept Videos
Bacterial Phylum Spirochaetes
416
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
416
Synthetic Biology
5.4K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Golden rice
Golden rice is a genetically modified...
5.4K

