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Updated: Dec 18, 2025

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
Published on: August 16, 2021
Impact of UDST: A step forward to end TB
Amit Kumar Sharma1, Sunil Vijay1, R B Mathur1
1Jhalawar Hospital and Medical College, Jhalawar, Rajasthan, India.
Background:
India is determined to eliminate TB by 2025 despite being a high burden country. Revised National Tuberculosis Control Programme (RNTCP) is being strengthened with introduction of Universal Drug Susceptibility Testing (UDST) for Rifampicin to achieve the elimination status.
Methodology:
We used a before-after comparison of baseline and intervention periods (12 months each) and analyzed data viz CBNAAT performed and case detection for both drug sensitive and drug resistant TB cases.
Results:
After implementation of Universal DST, CBNAAT performed raised from 1252 to 3137 (increased by 2.5 times); Rif sensitive cases detected raised from 458 to 1241 (increased by 2.7 times) and Rif resistant cases detected raised from 54 to 82 (increased by 1.5 times) during baseline period (2017) and intervention period (2018).
Conclusion:
We conclude that introduction of UDST for Rifampicin in RNTCP has given a significant impact with increased case detection in our study.
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