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The Importance of Tumor Length in Needle Biopsies of the Prostate
1VA and Duke University Medical Centers, Durham, NC.
Objectives:
To form a composite predictor variable that combines the effects of tumor length, serum prostate-specific antigen (PSA), and International Society of Urologic Pathologists (ISUP) grade on the observation of adverse prostatectomy pathology.
Methods:
Logistic regression analysis was used to demonstrate how tumor length, serum PSA, and ISUP grade related to adverse prostatectomy results and to derive weighting factors for a composite variable, cx.
Results:
The composite variable, cx, relates closely to adverse prostatectomy results as well as to observed PSA failure.
Conclusions:
The composite variable cx uses preoperative information that may allow the sorting of patients into low, intermediate, and high risk for adverse outcomes after prostatectomy.
