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Updated: Dec 18, 2025
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Published on: October 12, 2012
A new location for pediatric immunoglobulin G4 related disease: the biceps muscle
Semanur Özdel1, Mesiha Ekim1, Gülşah Kaygusuz2
1Divisions of Pediatric Rheumatology, Ankara University Faculty of Medicine, Ankara.
Background:
Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a systemic disorder of unknown etiology characterized by elevated serum IgG4 and tissue infiltration of IgG4-positive plasma cells. The disease was described in the pancreas, aorta, thyroid, salivary glands, periorbital tissues, kidneys, pericardium and lymph nodes.
Case:
Here in, we report a first pediatric case report of IgG4-related disease who presented with a mass in skeletal muscle i.e., biceps muscle.
Conclusion:
To the best of our knowledge, the involvement in skeletal muscle has previously not been reported in children.
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