The vertebrate epithelial apical junctional complex: Dynamic interplay between Rho GTPase activity and cell

Covadonga Díaz-Díaz1, Gabriel Baonza1, Fernando Martín-Belmonte1

  • 1Program of Tissue and Organ Homeostasis, Cellular Architecture, and Organogenesis Unit, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain.

Summary

Rho GTPases are crucial for epithelial tissue development and adult homeostasis. These proteins regulate cell junctions, maintaining the integrity and protective barrier function of epithelial cells.

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