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Establishment of a Clinic-based Biorepository
Published on: May 29, 2017
Building an I2B2-Based Population Repository for Clinical Research
Lydia González1, David Pérez-Rey1, Enrique Alonso1
1Biomedical Informatics Group, Artificial Intelligence Department, E.T.S.I. Informáticos, Universidad Politécnica de Madrid, Spain.
Abstract:
The present work provides a real-world case of the connection process of a hospital, 12 de Octubre University Hospital in Spain, to the TriNetX research network, transforming a compilation of disparate sources into a single harmonized repository which is automatically refreshed every day. It describes the different integration phases: terminology core datasets, specialized sources and eventually automatic refreshment. It also explains the work performed on semantic normalization of the involved clinical terminologies; as well as the resulting benefits the InSite platform services have enabled in the form of research opportunities for the hospital.
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