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Updated: Dec 17, 2025

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A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
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An "in silico" Bench to Bedside Approach to Investigating Sepsis Biomarkers
Grace O'Mahony1, Christopher Hawthorne1, Karl McQuaid1
1Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Studies in Health Technology and Informatics
|June 24, 2020
Abstract:
Sepsis results in various patient complications and is due to a heightened inflammatory response against infection. This condition requires further exploration of biomarkers. We employed an "in silico" method comprised of text-mining and additionally clinical validation through the Medical Information Mart for Intensive Care. We highlight that Factor VIII shows potential as a pertinent septic shock biomarker.

