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Updated: Dec 17, 2025

Harnessing the Bioorthogonal Inverse Electron Demand Diels-Alder Cycloaddition for Pretargeted PET Imaging
Published on: February 3, 2015
Biotinylated platinum(ii) metallacage towards targeted cancer theranostics
Xingchen Wang1, Qi Su2, Zeyuan Zhang1
1State Key Laboratory for Mechanical Behavior of Materials, Shaanxi International Research Center for Soft Matter, School of Materials Science and Engineering, Xi'an Jiaotong University, Xi'an 710049, P. R. China. mingming.zhang@xjtu.edu.cn.
Abstract:
A biotinylated metallacage was prepared via metal-coordination-driven self-assembly, combining fluorescence, anti-cancer and targeted properties into a single entity. The metallacage was successfully employed for targeted cell imaging and therapy, offering a platform for cancer theranostics.
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