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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Nivolumab for Metastatic Cutaneous Squamous Cell Carcinoma
Marcos Oro-Ayude1, Hae Jin Suh-Oh1, Victor Sacristán-Santos2
1Department of Dermatology, University Hospital of Pontevedra, Pontevedra, Spain.
Abstract:
Nivolumab is a programmed death receptor 1 (PD-1) inhibitor. It is part of a group of drugs known as immune checkpoint blockers, which enable potent and durable T-cell responses against several tumors. We report the case of a patient with a metastatic squamous cell carcinoma, who is being treated with nivolumab. This patient achieved a complete response and continues treatment without progression signs, supporting the notion that PD-1 inhibition can induce long-term remission and is well tolerated in this type of patient.
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