Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hydrogen generation promoted by single-atom-based thermochemical catalysts.

Nature reviews. Chemistry·2026

Same author

Spatial Engineering of Gas Diffusion Layers Overcomes Mass Transport Limitations in Fuel Cells.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Advanced Technologies for Characterizing and Detecting Battery Thermal Failure: A Review.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

battery_xct_workflows: extracting quality metrics from X-ray computed tomography of Li-ion cells.

MethodsX·2026

Same author

Harnessing Controlled Dealloying-Support Coupling for Ultrastable PtNi Catalysts in PEMFC Applications.

Angewandte Chemie (International ed. in English)·2026

Same author

Advanced Characterization and Rejuvenation of End-Of-Life Lithium-Ion Anodes: Toward the Development of a Green Upcycling Route.

Small (Weinheim an der Bergstrasse, Germany)·2026

Search research articles

Related Experiment Video

Updated: Dec 17, 2025

Failure Analysis of Batteries Using Synchrotron-based Hard X-ray Microtomography

Failure Analysis of Batteries Using Synchrotron-based Hard X-ray Microtomography

Published on: August 26, 2015

Resolving Li-Ion Battery Electrode Particles Using Rapid Lab-Based X-Ray Nano-Computed Tomography for High-Throughput

Thomas M M Heenan^1,2, Alice V Llewellyn^1,2, Andrew S Leach^1,2

¹Electrochemical Innovation Lab, Department of Chemical Engineering UCL London WC1E 7JE UK.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

|June 30, 2020

Summary

High-throughput nano-CT enables rapid 3D characterization of battery cathode powders. This method identifies internal voids that limit energy density and promote degradation, impacting electric vehicle performance.

Keywords:

X‐ray CT electrodes, Li‐ion metallurgy powder

More Related Videos

Characterization of Electrode Materials for Lithium Ion and Sodium Ion Batteries Using Synchrotron Radiation Techniques

Characterization of Electrode Materials for Lithium Ion and Sodium Ion Batteries Using Synchrotron Radiation Techniques

Published on: November 11, 2013

Nanoscale Characterization of Liquid-Solid Interfaces by Coupling Cryo-Focused Ion Beam Milling with Scanning Electron Microscopy and Spectroscopy

Nanoscale Characterization of Liquid-Solid Interfaces by Coupling Cryo-Focused Ion Beam Milling with Scanning Electron Microscopy and Spectroscopy

Published on: July 14, 2022

Related Experiment Videos

Last Updated: Dec 17, 2025

Failure Analysis of Batteries Using Synchrotron-based Hard X-ray Microtomography

Failure Analysis of Batteries Using Synchrotron-based Hard X-ray Microtomography

Published on: August 26, 2015

Characterization of Electrode Materials for Lithium Ion and Sodium Ion Batteries Using Synchrotron Radiation Techniques

Characterization of Electrode Materials for Lithium Ion and Sodium Ion Batteries Using Synchrotron Radiation Techniques

Published on: November 11, 2013

Nanoscale Characterization of Liquid-Solid Interfaces by Coupling Cryo-Focused Ion Beam Milling with Scanning Electron Microscopy and Spectroscopy

Nanoscale Characterization of Liquid-Solid Interfaces by Coupling Cryo-Focused Ion Beam Milling with Scanning Electron Microscopy and Spectroscopy

Published on: July 14, 2022

Area of Science:

Materials Science
Nanotechnology
Electrochemistry

Background:

Quality control for powders requires high-throughput 3D particle screening.
Traditional X-ray computed tomography (CT) methods are too slow for in-line analysis.
Synchrotron facilities offer speed but lack accessibility for routine checks.

Purpose of the Study:

To develop a rapid 3D characterization method for powder samples.
To enable high-throughput analysis of next-generation battery cathode materials.
To identify microstructural features impacting battery performance.

Main Methods:

Utilized nano-CT with full-field transmission X-ray microscopy and zone-plate optics.
Developed a novel sample preparation and high-throughput scanning procedure.
Analyzed lithium nickel manganese cobalt oxide (NMC811 and NMC622) cathode particles.

Main Results:

Achieved 3D characterization of powder samples in minutes, a significant speed improvement.
Successfully identified internal voids within NMC811 and NMC622 particles.
Demonstrated the capability to analyze diverse particle morphologies.

Conclusions:

The developed nano-CT method is suitable for rapid, in-line quality control of battery materials.
Internal voids detected can limit energy density and accelerate degradation in lithium-ion batteries.
This technique has implications for improving electric vehicle range and battery longevity.