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Two novel cyclohexanone-monocyclic polycyclic polyprenylated acylphloroglucinols from Garcinia multiflora fruits
Haida Teng1, Ziyu Ma1, Hongli Teng2
1College of Chemistry and Material Sciences, South-Central University for Nationalities, Wuhan, P.R. China.
Abstract:
Two novel cyclohexanone-monocyclic polyprenylated acylphloroglucinol (C-MPAP) derivatives, named norgarmultinones A (1) and B (2), were isolated from the fruits of Garcinia multiflora. Their structures were clarified by NMR, HRESIMS and calculated electronic circular dichroism (ECD) spectra. Compound 2 is the first example of naturally occurring C-MPAPs containing tetrahydropyran moiety by the cyclization of an enolic hydroxyl with an isogeranyl side chain. The reasonable biosynthetic routes of 1 and 2 were also put forward.
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