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Updated: Dec 16, 2025

Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
Tuning the properties of atomically precise gold nanoclusters for biolabeling and drug delivery
Man-Man Xu1, Tong-Tong Jia1, Bingjie Li2
1Green Catalysis Center and College of Chemistry, Zhengzhou University, Zhengzhou 450001, China. xuelizhao@zzu.edu.cn zangsqzg@zzu.edu.cn.
Abstract:
A structure-determined gold-levonorgestrel nanocluster, Au10(C21H27O2)10 (Au10NC), has been obtained via solvent induced crystal transformation from Au8(C21H27O2)8 (Au8NC), accompanied by a fluorescence color change from green to yellow. A cationic polymer, poly(allylamine hydrochloride) (PAH), was chosen to assemble with Au10NC to prepare monodisperse and stable particles (Au10NC-PAH) with an increased quantum yield of 49.8%. The as-fabricated Au10NC-PAH realized effective antibody-mediated actin imaging and sustained drug release.
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