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Updated: Dec 16, 2025

Design, Synthesis, and Photochemical Properties of Clickable Caged Compounds
Published on: October 15, 2019
A new supramolecular catalytic system: the self-assembly of Rh8 cage host anthracene molecules for [4 + 4]
Wei-Bin Yu1, Feng-Yi Qiu, Po Sun
1Analysis and Testing Central Facility, Institute of Molecular Engineering and Applied Chemistry, Engineering Research Institute, Anhui University of Technology, Maanshan 243002, P.R.China. yuweibin@ahut.edu.cn.
Abstract:
The supramolecular assembly, used as a molecular reactor, is of great significance in host-guest chemistry. In this work, we used a tetratopic pyridyl ligand as a building block to hierarchically combine a slightly twisted cuboid with half-sandwich rhodium fragments. The cuboid directionally self-assembled hydrophobic pockets that can encapsulate conjugated molecules like anthracene (ANT) as guests in solutions, by supramolecular interactions including hydrogen bonding and hydrophobic interactions. The array of the ANT molecules in the confined pockets was subjected to a [4 + 4] photocycloaddition reaction under UV light irradiation as an external stimulus in a methanol solution. Furthermore, the mechanism underlying the process was proposed. The cuboid was fully characterized by 1H NMR, single-crystal X-ray diffraction (SCXRD), and mass spectrometry (MS), and its host-guest and cycloaddition processes were monitored by 1H NMR spectroscopy and UV-visible spectrophotometry.
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