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Management of cutaneous vasculitis
Robert G Micheletti1, Christian Pagnoux2
1Departments of Dermatology and Medicine, University of Pennsylvania, 3400 Civic Center Blvd, 7 South, Room 724, Philadelphia, PA 19104, United States.
Presse Medicale (Paris, France : 1983)
|July 10, 2020
Summary
Most isolated cutaneous vasculitis cases resolve spontaneously. Severe or chronic cases may require systemic treatments like oral glucocorticoids, colchicine, dapsone, azathioprine, or hydroxychloroquine, with ongoing research for optimal therapies.
Area of Science:
- Dermatology
- Rheumatology
- Immunology
Background:
- Cutaneous vasculitis includes skin manifestations of systemic diseases and isolated forms.
- Terms like "cutaneous leukocytoclastic vasculitis" are imprecise but commonly used.
- Management guidelines for skin-limited vasculitis are lacking.
Purpose of the Study:
- To review the management of skin-limited and single-organ cutaneous vasculitis.
- To discuss treatment options for severe, chronic, or recurrent cases.
- To highlight the need for further research in effective therapies.
Main Methods:
- Review of existing literature on cutaneous vasculitis management.
- Discussion of treatment strategies based on disease severity.
- Identification of potential systemic therapies.
Main Results:
- Most isolated cutaneous vasculitis cases are self-limited and require no systemic treatment.
- Oral glucocorticoids may be used short-term for severe symptoms.
- Longer-term options include colchicine, dapsone, azathioprine, and hydroxychloroquine.
Conclusions:
- Treatment for cutaneous vasculitis should be tailored to disease severity.
- Further high-quality studies, including randomized trials, are essential.
- Determining the most effective therapies for skin-limited vasculitis remains an area for investigation.
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