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Evidence-Based Practical Guidance for the Antithrombotic Management in Patients With Coronavirus Disease (COVID-19)

Eduardo Ramacciotti1,2,3, Ariane Scarlatelli Macedo2, Rodrigo Bruno Biagioni4

  • 1Hospital Christóvão da Gama, Grupo Leforte, Santo André, São Paulo, Brazil.

Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
|July 11, 2020
PubMed

Insights

This guidance offers physicians evidence-based strategies for managing antithrombotic therapy in patients with coronavirus disease 2019 (COVID-19). It focuses on optimizing clinical decisions for thrombosis prevention and treatment in this patient population.

Area of Science:

  • Cardiology
  • Hematology
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19) is associated with a significant risk of thrombotic events.
  • Optimal antithrombotic strategies for COVID-19 patients remain an evolving area of clinical practice.

Purpose of the Study:

  • To provide clear, evidence-based clinical guidance for managing antithrombotic strategies in patients with COVID-19.
  • To support physicians in making informed decisions regarding anticoagulation and antiplatelet therapy.

Main Methods:

  • Consensus-based recommendations derived from a review of current best evidence.
  • Endorsement by major national and international societies in thrombosis, hemostasis, angiology, and vascular surgery.

Main Results:

  • The guidance addresses the use of antithrombotic agents in various clinical scenarios of COVID-19.
  • It outlines strategies for prophylaxis, treatment, and management of bleeding complications.

Conclusions:

  • Standardized, evidence-based antithrombotic management is crucial for improving outcomes in COVID-19 patients.
  • This practical guidance aims to standardize care and reduce thrombotic complications.

Keywords:
SARS-CoV-2anticoagulantsantiplateletsantithrombotic therapycoronavirus disease 2019thrombosis

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