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Percutaneous cannulation for extracorporeal membrane oxygenation (ECMO): A method for pig experimental models
Caroline Fritz1, Nicolas Viault1, Baptiste Fohlen1
1Department of Anesthesia and Intensive Care Medicine, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.
Methodsx
|July 17, 2020
Summary
This study presents a percutaneous method for extracorporeal membrane oxygenation (ECMO) cannulation in pigs, offering a less invasive approach for experimental models of critical conditions.
Area of Science:
- Veterinary Medicine
- Surgical Techniques
- Cardiovascular Research
Background:
- Pigs are common models for cardiogenic shock, cardiac arrest, and acute lung injury requiring extracorporeal membrane oxygenation (ECMO).
- Percutaneous cannulation offers advantages over surgical methods, including reduced trauma and bleeding.
- Pig anatomy, specifically the femoral artery, presents challenges for percutaneous access.
Purpose of the Study:
- To describe a feasible percutaneous ECMO cannulation method for pigs.
- To establish a simple and rapid technique for experimental models.
- To identify predictable complications associated with the method.
Main Methods:
- Utilized the Seldinger technique for percutaneous cannulation.
- Employed a standard percutaneous cannulation kit.
- Adapted the technique for the anatomical challenges of the pig femoral artery.
Main Results:
- Demonstrated the feasibility of percutaneous ECMO cannulation in pigs.
- Established a simple and rapid method suitable for non-cardiac surgeons.
- Identified and summarized predictable complications.
Conclusions:
- Percutaneous ECMO cannulation using the Seldinger technique is achievable in pigs.
- This method provides a less invasive alternative for creating experimental models.
- Understanding potential complications is crucial for successful implementation.
