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Temporal-lobe abnormalities in thanatophoric dysplasia
1Program in Developmental Pathology, Brown University, Providence, RI.
Pediatric Neuroscience
|January 1, 1988
Summary
Thanatophoric dysplasia (TD) is associated with abnormal hippocampal development. Abnormalities in the temporal lobe suggest a critical developmental window for TD-related brain malformations.
Area of Science:
- Neuroscience
- Developmental Biology
- Genetics
Background:
- Thanatophoric dysplasia (TD) is a severe skeletal disorder.
- Brain abnormalities are often observed in TD, but hippocampal development is not well understood.