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Electrosprayed Alginate Nanoparticles as CRISPR Plasmid DNA Delivery Carrier: Preparation, Optimization, and

Batoul Alallam1, Sara Altahhan2, Muhammad Taher1

  • 1Department of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan 25200, Malaysia.

Pharmaceuticals (Basel, Switzerland)
|July 26, 2020
PubMed
Summary

Researchers developed alginate nanoparticles (ALG NPs) for delivering CRISPR-Cas9 gene editing tools. These nanoparticles successfully edited a target gene in cells, showing promise for future therapeutic applications.

Keywords:
CRISPR-associated protein (Cas9)alginateclustered regularly interspaced short palindromic repeats (CRISPR)gene deliverynanoparticlestransfection

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