Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

8.8K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
8.8K
Mitochondrial Membranes01:45

Mitochondrial Membranes

16.1K
A single mitochondrion is a bean-shaped organelle enclosed by a double-membrane system. The outer membrane of mitochondria is smooth and contains many porins - the integral membrane transporters. Porins enable free diffusion of ions and small uncharged molecules through the outer mitochondrial membrane but limit the transport of molecules larger than 5000 Daltons. Further, the outer mitochondrial membrane forms a unique structure called membrane contact sites with other subcellular organelles,...
16.1K
Mitochondria01:37

Mitochondria

18.9K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
18.9K
Translocation of Proteins into the Mitochondria01:19

Translocation of Proteins into the Mitochondria

11.5K
Mitochondrial precursors are translocated to the internal subcompartments via independent mechanisms involving distinct protein machineries called translocases.
Sorting of outer membrane proteins:
Mitochondrial outer membrane proteins are of two types: the transmembrane, beta-barrel porins, and the membrane-anchored, alpha-helical proteins. Beta-barrel porin precursors are translocated by the TOM complex and inserted into the outer mitochondrial membrane by the SAM complex. In contrast,...
11.5K
Protein Import into the Peroxisomes01:27

Protein Import into the Peroxisomes

4.9K
Cells contain membrane-bound organelles called peroxisomes that oxidize organic molecules by transferring hydrogen atoms to oxygen, producing hydrogen peroxide. Peroxisomes enzymatically convert the released hydrogen peroxide into water and oxygen.
Peroxisomal Protein Import:
Peroxisomes lack the genetic machinery required to code for their own proteins. Hence, most peroxisomal membrane, lumenal and transmembrane proteins are synthesized in the cytoplasm or ER and transported to the peroxisome...
4.9K
Mitochondrial Protein Sorting01:39

Mitochondrial Protein Sorting

5.5K
Mitochondria are double-membrane organelles of the eukaryotes involved in cellular metabolism, signaling, ATP synthesis, and programmed cell death.  Each of these processes requires specific proteins and enzymes that must be correctly sorted to the right mitochondrial subcompartment for the proper functioning of the organelle.
Most of these mitochondrial proteins are encoded by the nucleus and imported to the mitochondria as unfolded or loosely folded precursors. Mitochondrial precursors...
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Coordination Between Treg Cells and Bifidobacterium in the Immune-Bacterial Network of Human Colostrum.

Journal of immunology research·2026
Same author

Impact of a UV-C Multiemitter Disinfection System on Hospital Environmental Bioburden and Inactivation of Clinically Relevant Pathogens.

Pathogens (Basel, Switzerland)·2026
Same author

Association between adipokines and glycemia in children under age 8: the PROGRESS cohort of Mexico.

medRxiv : the preprint server for health sciences·2026
Same author

First Trimester Vitamin D Deficiency and Risk of Gestational Diabetes Mellitus in a Mexican Cohort.

Nutrients·2026
Same author

Depression and Anxiety During Pregnancy in Mexican Women: Prevalence and Associated Factors in the OBESO Cohort Study.

Journal of clinical medicine·2025
Same author

Genetic Diversity of <i>Stenotrophomonas maltophilia</i> and Clonal Transmission (ST92) in Critical Care Units at Hospital Juárez de México: MLST and Virulence Profiling.

Pathogens (Basel, Switzerland)·2025
Same journal

Correction: Pramesthi et al. Evaluating the Impact of Indonesia's National School Feeding Program (ProGAS) on Children's Nutrition and Learning Environment: A Mixed-Methods Approach. <i>Nutrients</i> 2025, <i>17</i>, 3575.

Nutrients·2026
Same journal

Correction: Huang et al. Correlation Study Between Dietary Behaviors, Lifestyle, and Psychological Problems in Chinese Children Aged 3-7. <i>Nutrients</i> 2025, <i>17</i>, 176.

Nutrients·2026
Same journal

Association of Dietary Animal and Plant Protein Composition with All-Cause Mortality: 24-Year Population-Based Cohort Study.

Nutrients·2026
Same journal

Phytochemistry, Bioavailability, and Molecular Mechanisms Underlying Multitarget Anticancer Activity of <i>Aloe vera</i>.

Nutrients·2026
Same journal

A Comparison of the Interstitial and Blood Glucose Responses Following Consumption of Different Carbohydrate-Containing Beverages in Humans: A Randomised Controlled Trial.

Nutrients·2026
Same journal

Across Kingdoms: The Bacteriome, Mycobiome, and Virome in Autoimmune Diseases: Mechanistic Insights, Therapeutic Perspectives, and the Emerging Role of COVID-19.

Nutrients·2026
See all related articles

Related Experiment Video

Updated: Dec 13, 2025

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
03:19

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

662

Nutrients, Mitochondrial Function, and Perinatal Health.

Ameyalli M Rodríguez-Cano1,2, Claudia C Calzada-Mendoza1, Guadalupe Estrada-Gutierrez3

  • 1Section for Postgraduate Studies and Research, Higher School of Medicine, Instituto Politécnico Nacional, Mexico City 11340, Mexico.

Nutrients
|July 26, 2020
PubMed
Summary
This summary is machine-generated.

Maternal nutrition impacts mitochondrial function during pregnancy. Adequate macronutrients and micronutrients are crucial for healthy pregnancy outcomes and infant health, preventing adverse effects linked to mitochondrial dysfunction.

Keywords:
dietmacronutrientsmicronutrientsmineralspregnancyvitamins

More Related Videos

Analysis of Brain Mitochondria Using Serial Block-Face Scanning Electron Microscopy
07:47

Analysis of Brain Mitochondria Using Serial Block-Face Scanning Electron Microscopy

Published on: July 9, 2016

14.5K
Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
09:40

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

Published on: January 19, 2017

12.0K

Related Experiment Videos

Last Updated: Dec 13, 2025

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
03:19

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

662
Analysis of Brain Mitochondria Using Serial Block-Face Scanning Electron Microscopy
07:47

Analysis of Brain Mitochondria Using Serial Block-Face Scanning Electron Microscopy

Published on: July 9, 2016

14.5K
Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
09:40

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

Published on: January 19, 2017

12.0K

Area of Science:

  • Mitochondrial biology and physiology
  • Nutritional science and metabolism
  • Reproductive health and developmental biology

Background:

  • Mitochondria are vital organelles regulating cellular energy and key activities.
  • Pregnancy involves heightened nutritional demands impacting maternal and fetal metabolism.
  • Mitochondrial function varies between healthy and complicated pregnancies.

Purpose of the Study:

  • To review the role of macronutrients and micronutrients in mitochondrial function during pregnancy.
  • To explore the influence of nutrient availability on maternal and infant health outcomes.
  • To highlight the link between nutrient-induced mitochondrial dysfunction and adverse pregnancy outcomes.

Main Methods:

  • Literature review synthesizing current research on nutrition and mitochondria in pregnancy.
  • Analysis of studies investigating the impact of macronutrient and micronutrient status on mitochondrial processes.
  • Examination of evidence linking nutrient deficiencies or excesses to pregnancy complications.

Main Results:

  • Excessive macronutrient intake can cause oxidative stress and mitochondrial dysfunction.
  • Micronutrients are essential for mitochondrial energy metabolism and antioxidant defense.
  • Inadequate nutrient intake may impair energy supply, one-carbon metabolism, and epigenetic regulation.
  • Nutrient-related mitochondrial dysfunction can negatively affect maternal and infant health.

Conclusions:

  • Maternal nutrition critically influences mitochondrial health throughout pregnancy.
  • Optimizing macronutrient and micronutrient intake is essential for supporting fetal development and maternal well-being.
  • Mitochondrial dysfunction stemming from nutritional imbalances poses risks for adverse pregnancy outcomes and long-term infant health.