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Updated: Jun 23, 2026

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3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects
Published on: August 4, 2020
A Procedure for Designing Custom-Made Implants for Forehead Augmentation in People Suffering from Apert Syndrome
Marco Mandolini1, Manila Caragiuli2, Agnese Brunzini2
1Department of Industrial Engineering and Mathematical Sciences, Università Politecnica delle Marche, Via Brecce Bianche 12, 60131, Ancona, Italy. m.mandolini@univpm.it.
Journal of Medical Systems
|July 29, 2020
Summary
This study introduces a novel method for designing custom forehead implants for Apert syndrome patients with frontal bone deficiency. The patient-specific implants ensure an accurate fit, improving surgical outcomes.
Area of Science:
- Craniofacial surgery
- Biomedical engineering
- Medical imaging
Background:
- Apert syndrome often results in frontal bone deficiency, necessitating reconstructive surgery.
- Current methods for custom implant design can be complex and time-consuming.
Purpose of the Study:
- To present a new methodological procedure for designing patient-specific implants for forehead augmentation in Apert syndrome.
- To utilize anatomical reconstruction and constrained deformation for accurate implant modeling.
Main Methods:
- Applied anthropometric theory and cranial landmark identification for reference skull selection.
- Employed constrained deformation and free-form modeling for patient-specific implant design.
- 3D printing and comparison with a surgeon-crafted model to validate accuracy.
Main Results:
- Developed a reproducible methodology for custom implant design.
- Virtual modeling and 3D printing of three implants for pre-surgical evaluation.
- Negligible deviations between designed implants and the reference model, meeting surgical requirements.
Conclusions:
- The proposed method effectively designs accurate, custom-made implants for forehead reconstruction in Apert syndrome.
- This approach offers a reliable solution for addressing frontal bone deficiencies with patient-specific implants.

