Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Interfacial Electrochemical Methods: Overview01:06

Interfacial Electrochemical Methods: Overview

Interfacial electrochemical methods focus on the phenomena occurring at the boundary between an electrode and a solution, as opposed to bulk methods that concentrate on the solution's overall properties. These interfacial methods are classified as either static or dynamic based on the presence of a nonzero current in the electrochemical cell and the consistency of analyte concentrations. Static methods, such as potentiometry, measure the cell's potential without any significant current passing...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Capillary ratchets activated by interfacial flows for versatile torque generation and microassembly.

Science advances·2026
Same author

IrTMes - a stable SABRE catalyst for the hyperpolarization of [1-<sup>13</sup>C]-pyruvate.

The Analyst·2026
Same author

Miniaturization and Optimization of NMR Shimsets Allow Efficient Field Shimming.

Analytical chemistry·2026
Same author

Minimalist optical system for achromatic imaging within extended field of view based on monolithic integrated meta-axicon cluster.

Light, science & applications·2026
Same author

Finite elements and moving asymptotes accelerate quantum optimal control-FEMMA.

The Journal of chemical physics·2026
Same author

Rapid RASER MRI.

Angewandte Chemie (International ed. in English)·2026

Related Experiment Video

Updated: Jun 19, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.3K

An NMR-compatible microfluidic platform enabling in situ electrochemistry.

Hossein Davoodi1, Nurdiana Nordin2, Lorenzo Bordonali1

  • 1Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz Platz 1, 76344 Eggenstein-Leopoldshafen, Germany. neil.mackinnon@kit.edu vlad.badilita@kit.edu.

Lab on a Chip
|August 1, 2020
PubMed
Summary
This summary is machine-generated.

Researchers integrated microfluidic devices with nuclear magnetic resonance (NMR) by designing novel electrode geometries. This approach minimizes signal degradation, enabling enhanced NMR analysis of electrochemical processes like chitosan deposition.

More Related Videos

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation
08:27

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Published on: August 28, 2017

5.7K
Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

12.3K

Related Experiment Videos

Last Updated: Jun 19, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.3K
Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation
08:27

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Published on: August 28, 2017

5.7K
Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

12.3K

Area of Science:

  • Analytical Chemistry
  • Microfluidics
  • Nuclear Magnetic Resonance Spectroscopy

Background:

  • Integrating microfluidic devices with nuclear magnetic resonance (NMR) offers advanced sample handling and analysis capabilities.
  • Conductive structures, such as metallic electrodes, pose challenges in microfluidic NMR due to potential spectral and signal-to-noise ratio (SNR) degradation.
  • These challenges are amplified at the micro-scale, where electrode-induced distortions occupy a larger sample volume ratio.

Purpose of the Study:

  • To identify and validate an optimal electrode geometry for microfluidic devices that minimizes NMR spectral degradation.
  • To investigate the impact of electrode placement on NMR radiofrequency (RF) excitation performance and magnetic field homogeneity (B0).
  • To demonstrate the feasibility of using this integrated system for in situ NMR characterization of electrochemical processes.

Main Methods:

  • Utilized a combination of computational simulations and experimental validation to assess various electrode designs.
  • Developed microfluidic channels with metallic electrodes strategically placed in the side-walls.
  • Performed in situ monitoring of chitosan deposition using NMR spectroscopy within the microfluidic platform.

Main Results:

  • Identified a specific side-wall electrode geometry that performs comparably to systems without electrodes, preserving NMR spectral parameters.
  • Observed enhanced NMR RF excitation performance without compromising B0 homogeneity with the optimized electrode design.
  • Successfully demonstrated proof-of-concept for NMR characterization of in situ chitosan deposition, an electrochemical process.

Conclusions:

  • Optimized electrode placement in microfluidic channels can overcome NMR signal degradation issues.
  • Side-wall electrode integration enhances NMR performance and enables detailed analysis of microfluidic electrochemical processes.
  • This technology provides a powerful tool for real-time characterization of microscale electrochemical reactions.