Related Experiment Video
Updated: Dec 13, 2025

Author Spotlight: A New and Efficient Method for Comprehensive Metabolite Cytotoxicity Assessment of Triazole Pesticides in Plants
Published on: December 22, 2023
The biological detoxification of deoxynivalenol: A review
1Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, 110866, China.
Abstract:
Deoxynivalenol (DON), which is one of the most common mycotoxins produced by Fusarium species, is often found known to contaminated food and feed all around the world. It usually causes diarrhea, vomiting, and gastrointestinal inflammation in both humans and animals. At present, one promising method of dealing with this mycotoxin is to detoxify it biologically using microbes or enzymes. Some microorganisms have the ability to absorb or degrade mycotoxins before gastrointestinal absorption occurs. Many fungi and bacteria have been reported to be able to play a role in the biological detoxification of DON. In this review, the occurrence of DON in food and its toxic effects are presented and the mechanisms by which DON can be detoxified biologically are also discussed. Then, the progress made in detoxifying DON in recent years using fungi, bacteria, and enzymes is summarized in more detail. Future developments relating to DON detoxification are also evaluated. The overall purpose of this paper is to provide a reliable reference source for the biological detoxification of DON.
Related Concept Videos
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Drug Elimination: Overview
Excretion refers to removing a drug from the body, either in its unchanged form or as its metabolites. Nonvolatile and polar drugs are primarily excreted through the kidneys, with other pathways including bile, sweat, saliva, and milk. Volatile drugs such as anesthetic gases are excreted via the...
Drug Elimination: Non-Renal Routes
Prevention of Further Absorption of Poison
Drug Biotransformation: Overview
Drug Biotransformation: Overview

