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[Urinary infections caused by non-typhoid Salmonella]
A Carducci1, R Pierotti, G Aquino
1Università degli Studi di Pisa, Dipartimento di Biomedicina Sperimentale.
Abstract:
Between January 1986 and January 1989, 524 non-typhoid salmonella strains, of which 4 (0.8%) from urine, were isolated at the Microbiology Laboratory of Department of Biomedicine (University of Pisa). These strains were isolated from a man with systematic lupus erythematosus, from two little girls with structural defects of the lower urinary tract, and from a woman with ulcerous colitis. Except the last case, the others were associated with immunological or structural abnormalities that are thought to predispose to salmonella infections.
Insights
Non-typhoid Salmonella urinary tract infections are rare (0.8%). Underlying immune or structural abnormalities predispose individuals to these infections, as seen in lupus and urinary tract defect patients.
Area of Science:
- Microbiology
- Infectious Diseases
- Urology
Background:
- Non-typhoid Salmonella infections can occur in various body sites.
- Urinary tract infections (UTIs) are commonly caused by other bacteria.
- Salmonella UTIs are infrequently reported.
Observation:
- A study period of January 1986 to January 1989 at the University of Pisa Microbiology Laboratory.
- Isolation of 524 non-typhoid Salmonella strains.
- Four (0.8%) of these strains were isolated from urine samples.
Findings:
- The four urine isolates were from a patient with systemic lupus erythematosus, two young girls with lower urinary tract structural defects, and a woman with ulcerative colitis.
- Three of the four cases were linked to predisposing immunological or structural abnormalities.
- Systemic lupus erythematosus and congenital urinary tract defects are identified as risk factors.
Implications:
- Highlights the potential for non-typhoid Salmonella to cause urinary tract infections.
- Suggests that patients with specific immune deficiencies or structural urinary abnormalities are at higher risk.
- Underscores the importance of considering Salmonella in UTIs within susceptible patient populations.