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In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
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Updated: Dec 12, 2025

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions
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Peri-implantation intercourse does not lower fecundability.

Joseph B Stanford1, Jared L Hansen1, Sydney K Willis2

  • 1Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.

Human Reproduction (Oxford, England)
|August 7, 2020
PubMed
Summary
This summary is machine-generated.

Sexual intercourse during the implantation window does not reduce fecundability. This study found no association between intercourse in the implantation period and the ability to conceive, offering reassurance to couples trying to conceive.

Keywords:
conceptionday-specific probabilities of conceptionfecund windowfecundabilityfertile windowsexual intercoursetime to pregnancy

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Area of Science:

  • Reproductive Medicine
  • Human Fertility Studies
  • Obstetrics and Gynecology

Background:

  • Previous research suggested intercourse during the peri-implantation window (5-9 days post-ovulation) might decrease fecundability.
  • This potential association has implications for conception timing advice.

Purpose of the Study:

  • To investigate whether sexual intercourse during the implantation time window affects fecundability.
  • To provide evidence-based guidance for couples attempting to conceive.

Main Methods:

  • Prospective observational study (FERTILI) involving 661 women across five European countries (1992-1996).
  • Data collected via daily diaries on cervical mucus, basal body temperature, and coitus; ovulation estimated.
  • Bayesian fecundability model used to analyze 2606 cycles, adjusting for covariates.

Main Results:

  • No statistically significant association was found between intercourse in the implantation window and fecundability (adjusted FR 1.00; 95% CI: 0.76-1.13).
  • Sensitivity analyses confirmed these findings.
  • An inverse relationship was observed between intercourse frequency in the fecund window and the peri-implantation window.

Conclusions:

  • The current evidence does not support recommending avoidance of intercourse during the peri-implantation period for couples trying to conceive.
  • Findings may help alleviate concerns about conception timing around ovulation.