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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
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Percutaneous Interventions for Secondary Mitral Regurgitation
Mahboob Ali1, Satya S Shreenivas2, David N Pratt1
1University of Cincinnati, OH (M.A., D.N.P., D.R.L.).
Circulation. Cardiovascular Interventions
|August 8, 2020
Summary
Mitral regurgitation (MR) management is evolving with new percutaneous options. Understanding functional MR subtypes is crucial for selecting patients who will benefit most from these innovative treatments.
Area of Science:
- Cardiology
- Interventional Cardiology
- Heart Failure Management
Background:
- Mitral regurgitation (MR) is linked to ventricular dysfunction and high mortality.
- Current treatments include medical therapy, surgery, heart transplant, and ventricular assist devices.
- Advancements include edge-to-edge repair (MitraClip) and emerging catheter-based percutaneous options.
Purpose of the Study:
- To review the pathophysiology of functional mitral regurgitation.
- To discuss current and emerging percutaneous therapeutic options for functional MR.
- To highlight the importance of patient subgroup selection for novel device success.
Main Methods:
- Review of current literature on mitral regurgitation pathophysiology.
- Analysis of existing and investigational percutaneous mitral valve repair techniques.
- Discussion of clinical trial data and future directions for functional MR.
Main Results:
- Functional MR pathophysiology varies, with disproportionate vs. proportionate MR impacting outcomes.
- Percutaneous mitral valve repair offers promising alternatives for select patients.
- Successful deployment of new devices hinges on precise patient selection based on specific pathophysiology.
Conclusions:
- Understanding the nuances of functional mitral regurgitation is essential for optimizing percutaneous treatment outcomes.
- Novel percutaneous therapies are expanding treatment options for patients with functional MR.
- Ongoing clinical trials will further define the role of these interventions in heart failure management.
Keywords:
mitral regurgitationmitral valvemitral valve insufficiencypercutaneous mitral valve repairpercutaneous mitral valve replacementtranscatheter mitral valve replacementMore Related Videos
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