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Perioperative Anesthetic Management and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Grafting and

Ahmet Atlas1, İlker Tekin2, Yucel Yuksel3

  • 1Department of Anesthesiology and Reanimation, Harran University Medical Faculty, Sanliurfa, Turkey.

Transplantation Proceedings
|August 8, 2020
PubMed

Insights

Combined coronary artery bypass grafting (CABG) and kidney transplant in end-stage renal disease (ESRD) patients is feasible. This combined approach may improve outcomes compared to separate surgeries, reducing mortality and morbidity.

Area of Science:

  • Nephrology
  • Cardiology
  • Transplant Surgery

Background:

  • Cardiovascular disease is a leading cause of mortality and graft failure in end-stage renal disease (ESRD) patients.
  • Kidney transplant recipients face significant risks from cardiovascular complications.

Purpose of the Study:

  • To evaluate the safety and efficacy of combined coronary artery bypass grafting (CABG) and kidney transplant in a single session.
  • To compare outcomes of combined versus staged surgical approaches for ESRD patients with coronary artery disease.

Main Methods:

  • Retrospective study of 77 end-stage renal disease (ESRD) patients undergoing combined CABG and kidney transplant between May 2010 and September 2017.
  • Analysis of patient demographics, comorbidities (diabetes mellitus, hypertension), and perioperative outcomes.

Main Results:

  • The cohort was predominantly male (84.4%) with high rates of hypertension (90.9%) and diabetes mellitus (71.4%).
  • Mean postoperative outcomes included ICU stay of 3.4 days, extubation at 12.1 hours, and hospital stay of 11.6 days.
  • Transfusion requirements included 2.6 units of red blood cells and 2.1 units of fresh-frozen plasma.

Conclusions:

  • Combined CABG and kidney transplant in the same session is a viable approach for ESRD patients.
  • This combined strategy appears to offer improved outcomes regarding mortality and morbidity compared to separate surgical procedures.
Abstract

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