Antioxidants and Skin Protection.
María Herranz-López1, Enrique Barrajón-Catalán1
1Instituto de Biología Molecular y Celular (IBMC) and Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universitas Miguel Hernández (UMH), 03202 Elche, Spain.
Antioxidants (Basel, Switzerland)
|August 8, 2020
Summary
Natural products offer benefits for aged and damaged skin. Research explores their use in improving skin appearance and function.
Area of Science:
- Dermatology and Cosmeceutical Science
- Natural Product Chemistry
Background:
- Natural products have a long history in traditional medicine for skin health.
- Aging and skin damage present challenges for dermatological treatments.
- The efficacy of natural compounds for skin repair is an area of active research.
Discussion:
- Investigating the biochemical mechanisms of natural products on skin cells.
- Evaluating the safety and efficacy profiles of botanical extracts for topical application.
- Comparing the performance of natural ingredients against synthetic alternatives in skincare formulations.
Key Insights:
- Certain natural compounds demonstrate significant antioxidant and anti-inflammatory properties beneficial for skin.
- Topical application of specific plant-derived molecules can promote collagen synthesis and skin barrier repair.
- Evidence supports the role of natural products in mitigating signs of photoaging and environmental damage.
Outlook:
- Further clinical trials are needed to validate the therapeutic potential of novel natural products.
- Development of standardized extracts and delivery systems can enhance the bioavailability and effectiveness of natural ingredients.
- Integration of natural products into evidence-based skincare regimens holds promise for regenerative dermatology.
Related Concept Videos
01:20Radical Autoxidation
2.8K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
2.8K
01:19Pigmentation
4.0K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
4.0K
01:23Role of Skin in Vitamin D Synthesis
7.2K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.2K
01:18Surface Membrane Barriers
2.4K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
2.4K
01:17Oxidation of Phenols to Quinones
4.2K
In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
4.2K
01:25Introduction to the Integumentary System
12.6K
The integumentary system is the organ system that comprises the skin and its associated structures. It is the largest system in the human body and plays a crucial role in protecting and maintaining homeostasis. The integumentary system serves several functions including protection, regulation, sensation, and secretion.
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...
12.6K