Granular cell tumor in a child: A rare case report

Area of Science:

• Oncology
• Pathology
• Pediatric Neoplasms

Background:

• Granular cell tumors (GCTs) are rare soft tissue neoplasms, typically benign and originating from Schwann cells.
• GCTs most commonly occur in the head and neck region and are uncommon in pediatric patients.

Observation:

• A 6-year-old girl presented with a swelling over her left scapula.
• Surgical excision was performed, and microscopic examination revealed a tumor composed of cells with granular cytoplasm and oval to round nuclei.

Findings:

• Immunohistochemical analysis showed positive staining for S-100, CD68, neuron-specific enolase, calretinin, and inhibin A.
• The tumor exhibited characteristics consistent with a granular cell tumor.

Implications:

• This case highlights the occurrence of GCT in an atypical pediatric location (scapula).
• While typically benign with a good prognosis, the possibility of malignancy in GCTs, even in unusual sites, warrants consideration.