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Osteoporosis in Older Adults
Catherine Bree Johnston1, Meenakshi Dagar1
1Division of Geriatrics, General Internal Medicine, and Palliative Medicine, Department of Medicine, University of Arizona College of Medicine, Banner University Medical Center, 1501 North Campbell Avenue, Suite 7401, Tucson, AZ 85724-5801, USA.
The Medical Clinics of North America
|August 11, 2020
Summary
Osteoporosis prevention and screening are crucial for adults, especially women over 65. Effective pharmacologic therapies, including bisphosphonates, are available for treating osteoporosis and reducing fracture risk.
Area of Science:
- Geriatrics
- Endocrinology
- Public Health
Background:
- Osteoporosis and associated fractures significantly increase morbidity and mortality in older adults.
- Preventive measures and timely screening are essential for managing osteoporosis in the aging population.
Purpose of the Study:
- To provide guidance on osteoporosis prevention strategies for healthy adults.
- To outline screening recommendations for women and men.
- To discuss pharmacologic treatment options for osteoporosis.
Main Methods:
- Review of current clinical guidelines and evidence for osteoporosis screening.
- Analysis of available pharmacologic therapies for osteoporosis management.
- Consideration of patient-specific factors in treatment selection.
Main Results:
- Women aged 65 and older should be screened for osteoporosis.
- Screening in men should be considered based on risk factors; optimal intervals remain debated.
- Pharmacologic therapies, including bisphosphonates, denosumab, teriparatide, abaloparatide, romosozumab, and SERMs, are recommended for treatment.
Conclusions:
- Early detection and intervention are key to managing osteoporosis.
- Personalized pharmacologic therapy selection is crucial for effective osteoporosis treatment.
- Ongoing research is needed to refine screening protocols and treatment strategies.
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