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Acute Hormonal Responses to High-Intensity Interval Training in Hyperoxia
Giorgio Manferdelli1, Nils Freitag1, Kenji Doma2
1Institute of Cardiovascular Research and Sport Medicine, Department of Molecular and Cellular Sport Medicine, German Sport University, Cologne, Germany.
Journal of Human Kinetics
|August 11, 2020
Summary
High-intensity interval training in hyperoxia significantly increased cortisol levels in recreationally trained men compared to normoxia. Prolactin responses were similar, while vascular endothelial growth factor remained unchanged.
Area of Science:
- Exercise Physiology
- Sports Science
- Endocrinology
Background:
- High-intensity interval training (HIIT) is a popular exercise modality.
- The impact of hyperoxia on hormonal responses during HIIT requires further investigation.
- Understanding these responses is crucial for optimizing training protocols.
Purpose of the Study:
- To compare hormonal responses to HIIT under hyperoxic and normoxic conditions.
- To investigate changes in cortisol, prolactin, and vascular endothelial growth factor (VEGF).
- To assess the influence of increased fraction of inspired oxygen during HIIT.
Main Methods:
- Twelve recreationally trained men participated in a randomized crossover study.
- Participants completed two HIIT sessions on a cycle ergometer: one in hyperoxia (94% O2) and one in normoxia.
- Hormonal levels (cortisol, prolactin, VEGF) were measured pre- and post-exercise.
Main Results:
- Cortisol significantly increased in hyperoxia (61.4%) but not in normoxia (-1.3%).
- Prolactin increased in both conditions (hyperoxia: 118.1%, normoxia: 62.14%), with no significant difference between them.
- VEGF concentrations showed no statistically significant alterations in either condition.
Conclusions:
- A single session of HIIT in low-dose hyperoxia significantly elevates cortisol in recreationally trained individuals compared to normoxia.
- Hyperoxia had a smaller differential effect on prolactin and no significant effect on VEGF.
- These findings suggest hyperoxia may modulate stress hormone responses during HIIT.
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