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Endocrine evaluation and therapy of erectile dysfunction.
1Department of Urology, University of California School of Medicine, San Francisco.
The Urologic Clinics of North America
|February 1, 1988
Summary
Organic causes account for 30-50% of impotence cases. Evaluating male hypogonadism and the hormonal axis is key for endocrinologic impotence treatment, using gonadotropin assays and aiming for physiologic testosterone levels.
Area of Science:
- Endocrinology
- Urology
Background:
- Organic causes represent a significant portion (30-50%) of male impotence cases.
- Male hypogonadism and the reproductive hormonal axis are critical factors in endocrinologic impotence.
Purpose of the Study:
- To highlight the importance of understanding male hypogonadism and hormonal axis in impotence evaluation.
- To emphasize the role of gonadotropin assays in diagnosing testicular failure.
- To outline the goals of androgen replacement therapy.
Main Methods:
- Review of recent laboratory and clinical investigations.
- Analysis of diagnostic approaches for endocrinologic impotence.
- Discussion of therapeutic strategies including androgen replacement.
Main Results:
- Organic etiologies are prevalent in male impotence.
- Gonadotropin assays (FSH, LH) differentiate primary and secondary testicular failure.
- Androgen replacement aims for physiologic testosterone levels, avoiding hepatotoxicity.
Conclusions:
- Endocrinologic evaluation is crucial for a subset of impotence cases.
- Accurate diagnosis of testicular function aids treatment selection.
- Safe and effective androgen replacement is achievable.