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Related Experiment Video

Updated: Dec 12, 2025

Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy

Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy

Published on: January 22, 2018

Confrontation with a live subretinal parasite.

Simanta Khadka¹, Raghu Nandan, Sangita Pradhan

¹Bharatpur Eye Hospital, Bharatpur, Chitwan.

Nepalese Journal of Ophthalmology : a Biannual Peer-Reviewed Academic Journal of the Nepal Ophthalmic Society : NEPJOPH

|August 15, 2020

Summary

A rare case of a live subretinal worm, identified as Loa Loa, caused vision loss in a young man. Surgical removal successfully preserved the patient's vision.

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Last Updated: Dec 12, 2025

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Area of Science:

Ophthalmology
Parasitology
Tropical Medicine

Background:

Ocular parasitic infestations are a significant global cause of eye diseases.
Filarial and filarial-like nematodes are primary culprits in eye infections.

Observation:

A unique case involved a live, subretinal worm identified as Loa Loa in a young male patient.
The patient presented with unilateral vision loss and floaters, with a visible, mobile worm and retinal edema.

Findings:

Microscopic identification confirmed the parasite as Loa Loa.
Surgical extraction of the worm led to improved visual acuity from 3/60 to 6/12 within three months.

Implications:

Management of subretinal live worms is challenging and depends on parasite location and viability.
Prompt surgical intervention is crucial for worm removal and vision preservation in such cases.