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Clinical Profile of posterior segment in high Myopia
Raju Kaiti1, Birkha Bogati2, Ranjila Shyangbo3
1Department of Optometry, Nepal Eye Hospital, Tripureswor, Kathmandu, Nepal.
High myopia, common in Nepal, shows frequent fundus changes like tessellated fundus and peripapillary atrophy. Increased axial length and spherical error are key risk factors for these myopic changes.
Area of Science:
- Ophthalmology
- Public Health
- Medical Research
Background:
- Myopia is a growing global health concern, with prevalence projected to reach 4.7 billion by 2050.
- High myopia (<-5.00 D) increases the risk of irreversible blindness and complications like myopic maculopathy.
- Nepal has a high myopia prevalence (47.16%), necessitating studies on its impact.
Purpose of the Study:
- To assess fundus and optic nerve changes in high myopia among Nepalese individuals.
- To examine the association of these changes with age, gender, axial length, and mean spherical error.
Main Methods:
- A prospective, cross-sectional study involving 98 high myopic eyes (<-5.0 D or axial length ≥26.00 mm).
- Colored Fundus photography was used to evaluate posterior segment and optic disc changes.
- Multinomial logistic regression analyzed axial length and mean spherical error as risk factors.
Main Results:
- Tessellated fundus (57.1%) and peripapillary atrophy (40.8%) were the most common posterior segment changes.
- High myopic features were observed in 45.9% of the studied eyes.
- Increased axial length and mean spherical error were identified as significant risk factors for high myopic changes.
Conclusions:
- Myopic changes, including tessellated fundus and peripapillary atrophy, are frequent in the Nepalese high myopia population.
- Axial length and mean spherical error are significantly associated with the development of these fundus changes.
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