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Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
Published on: July 22, 2011
How to investigate a suspected immune deficiency in adults
Alexandros Grammatikos1, Philip Bright1, Rahul Bhatnagar2
1Department of Clinical Immunology, North Bristol NHS Trust, Bristol, UK.
Abstract:
Patients with immune deficiencies can present with variable clinical phenotypes. This often translates into a significant delay in their diagnosis, and resultant patient morbidity. This review summarises the most common types of immunodeficiency disorders, primary and secondary, along with their key features. It provides a structured approach for the clinician on when to suspect an immunodeficiency, the initial investigations pathway and when a specialist referral should be considered.
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