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Amniotic Membrane Transplantation in Ophthalmology: An Updated Perspective
1Manchester Royal Eye Hospital, Manchester University Foundation Trust, Manchester, UK.
Clinical Ophthalmology (Auckland, N.Z.)
|August 18, 2020
Summary
This review covers clinical uses of amniotic membrane transplantation (AMT) in ophthalmology. It details AMT
Area of Science:
- Ophthalmology
- Regenerative Medicine
- Tissue Engineering
Background:
- The ocular surface is susceptible to damage.
- Amniotic membrane (AM) possesses unique biological properties beneficial for ocular surface reconstruction.
- Current literature presents diverse applications of AM in ophthalmology.
Purpose of the Study:
- To review clinical applications of amniotic membrane transplantation (AMT) in ophthalmology.
- To elucidate the biological properties of amnion and its indications for use.
- To update on AM preservation and application methods.
Main Methods:
- Comprehensive literature search on PubMed using specific keywords.
- Inclusion of English-language articles, both reviews and original research.
- Focus on publications related to ophthalmology up to May 2020.
Main Results:
- AMT is utilized for various ophthalmic conditions, from common to less frequent uses.
- Evidence supports the efficacy of AMT in promoting ocular surface healing and regeneration.
- Updated information on AM preservation techniques and surgical application methodologies is presented.
Conclusions:
- AMT is a versatile therapeutic option in ophthalmology.
- Understanding AM's biological properties enhances its clinical utility.
- Standardized preservation and application methods are crucial for optimal outcomes.
