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Published on: June 21, 2021
Rapid SERS Detection of Thiol-Containing Natural Products in Culturing Complex
Yan Hong1, Rui Wang1, Zhuoran Jiang2
1School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu 610054, China.
Abstract:
Thiol-containing natural products possess a wide range of bioactivities. The burst of synthetic biology technology facilitates the discovery of new thiol-containing active ingredients. Herein, we report a sensitive, quick, and robust surface-enhanced Raman scattering technology for specific and multiplex detection of thiol-containing compounds without purification requirements and also indicating the thiols with different chemical environments. Using this platform, we successfully demonstrated the simultaneous detection of thiol-containing compounds from as low as 1 μM of analytes spiked in complex culture matrices.
