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Facial Transplants in Xenopus laevis Embryos
Published on: March 26, 2014
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Should We Consider Preparing Patients for Future Face Transplant when Managing Complex Facial Trauma?
Matthew R Zeiderman1, Joseph M Firriolo1, Dattesh R Dave1
1Division of Plastic Surgery, Department of Surgery, University of California at Davis, Sacramento, Calif.
Plastic and Reconstructive Surgery. Global Open
|August 18, 2020
Summary
Preparing patients with severe facial trauma for face transplantation is crucial. This case demonstrates successful pre-transplant reconstructive surgery, optimizing outcomes for complex craniomaxillofacial injuries.
Area of Science:
- Reconstructive Surgery
- Microsurgery
- Transplantation
Background:
- Face transplantation is an emerging procedure for severe facial defects.
- Optimal outcomes require meticulous pre-transplant preparation of the maxillofacial skeleton and soft tissues.
Purpose of the Study:
- To present a case of pre-transplant reconstructive surgery for a patient with extensive craniomaxillofacial trauma.
- To highlight the importance of this preparation for successful face transplantation.
Main Methods:
- Open reduction internal fixation of complex facial fractures (LeFort III, zygomaticomaxillary complex, maxilla, mandible).
- Reconstruction using titanium plates.
- Soft-tissue coverage with free anterolateral thigh perforator flaps and a fasciocutaneous flap.
- Management of flap complications including partial necrosis.
Main Results:
- Achieved stable bone reconstruction and soft-tissue coverage in a patient with severe ballistic facial injury.
- Patient was successfully discharged and subsequently underwent a face transplant.
- Demonstrated feasibility of complex pre-transplant reconstruction.
Conclusions:
- Pre-transplant reconstructive surgery is vital for patients with craniomaxillofacial trauma exceeding conventional limits.
- This approach enhances the potential for optimal face transplant outcomes.
- Minimizing flap donor site morbidity is a key consideration.
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