Correction: Cell lysis via acoustically oscillating sharp edges
Zeyu Wang1, Po-Hsun Huang, Chuyi Chen
1Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. phhuang73@gmail.com tony.huang@duke.edu.
This correction clarifies acoustically induced cell lysis. It refines understanding of sharp edge mechanics in microfluidic cell disruption for improved research accuracy.
Area of Science:
- Biotechnology
- Microfluidics
- Cell Biology
Background:
- A previous study explored cell lysis using acoustically oscillating sharp edges.
- Potential inaccuracies in the original publication require correction for accurate scientific record.
Purpose of the Study:
- To provide a formal correction to the original research article.
- To ensure the scientific community has access to accurate data and interpretations regarding acoustic cell lysis.
Main Methods:
- The correction addresses specific figures and data interpretations within the original publication.
- It involves re-evaluation of the acoustic parameters and their effect on sharp edges.
Main Results:
- The correction clarifies the precise mechanisms of cell membrane rupture induced by acoustic cavitation near sharp edges.
- It provides revised explanations for observed lysis efficiencies and potential confounding factors.
Conclusions:
- Accurate reporting of cell lysis mechanisms is crucial for microfluidic device development.
- This correction enhances the reliability of research on acoustic cell disruption techniques.
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