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Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
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Risk Factors for Progression of Distal Deep Vein Thrombosis

Shunichiro Fujioka1, Hirotoki Ohkubo1, Tadashi Kitamura1

  • 1Department of Cardiovascular Surgery, Kitasato University School of Medicine.

Circulation Journal : Official Journal of the Japanese Circulation Society
|August 21, 2020
PubMed

Insights

Conservative treatment may be suitable for distal deep vein thrombosis (DVT). Anticoagulation is recommended for patients with active cancer, prolonged bed rest, or high D-dimer levels to prevent clot extension.

Area of Science:

  • Vascular Medicine
  • Thrombosis Research

Background:

  • Optimal treatment for distal deep vein thrombosis (DVT) remains unclear.
  • Indications for anticoagulation therapy in distal DVT require further clarification.

Purpose of the Study:

  • Evaluate treatment outcomes for distal DVT patients.
  • Identify risk factors for DVT extension to proximal veins.
  • Determine appropriate indications for anticoagulation therapy.

Main Methods:

  • Retrospective analysis of 212 distal DVT patients treated conservatively with compression stockings.
  • Initial treatment without immediate anticoagulation.
  • Follow-up ultrasonography at 2 weeks and 3 months.

Main Results:

  • Thrombus disappearance occurred in 52% of patients after 3 months.
  • DVT extension to proximal veins occurred in 6.3% of patients.
  • Risk factors for extension included active cancer, prolonged bed rest, and D-dimer >8µg/mL.

Conclusions:

  • Conservative management is a viable option for select distal DVT patients.
  • Anticoagulation therapy should be considered for distal DVT patients with active cancer, prolonged bed rest, or elevated D-dimer levels.
Abstract

Keywords:
Anticoagulation therapyBed restD-dimer levelsDistal deep vein thrombosis

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