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Outbreak of Measles in a Residential Home for the Intellectually Disabled in Singapore in 2019
Valerie T J Koh1, Calvin J Chiew1, Sean Wei Xiang Ong1
1Valerie T. J. Koh, Calvin J. Chiew, Khine Nandar, Anne Lee, Kelly Foo, Rachael Pung, Zubaidah Said, and Vernon Lee are with the Communicable Diseases Division, Ministry of Health, Singapore. Sean Wei Xiang Ong, Tau Hong Lee, David Chien Lye, and Yee-Sin Leo are with the National Centre for Infectious Diseases, Singapore. Lin Cui, Yi Kai Ng, and Raymond Lin are with the National Public Health Laboratory, National Centre for Infectious Diseases, Singapore.
Abstract:
A measles outbreak involving 19 adults in a home for the intellectually disabled occurred in Singapore in 2019. Further investigation, including a serological survey, was conducted. Mass vaccination and infection control measures were implemented, terminating further secondary transmission. Seropositivity among residents aged 40 to 49 years (90.7%; 95% confidence interval = 78.4%, 96.3%) was lower than among the Singapore adult population (P < .001). This sheltered population, like others previously reported in the literature, had lower measles immunity than the general community, possibly because of limited social interaction. Targeted catch-up vaccination for similarly vulnerable populations should be considered.
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