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Updated: Dec 11, 2025

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
[Myopia in children]
1Service d'ophtalmologie de l'hôpital universitaire Necker Enfants-Malades, APHP, Centre de maladies rares OPHTARA1, 149, rue de Sèvres, 75015 Paris, France - Faculté de Médecine, université de Paris, Paris 75015, France - Unité Inserm UMRS 1138, équipe 17, Université Paris V Sorbonne Paris Cité, Paris, France.
Abstract:
Myopia is a refractive anomaly, a global public health issue, mainly due to an increase in axial length of the eyeball. Myopia is increasing worldwide with the appearance of a "myopia global growing epidemic". In children under 6 years old, 20 % have abnormalities, the most common of which are primarily refractive abnormalities, followed by strabismus and amblyopia. Myopia presents a major risk of complications, correlated with its severity, such as retinal detachment, retinal neovascularization, early cataracts and glaucoma. In children with high myopia, syndromic myopia must be explored. Early detection of myopia onset and progression is essential to myopia control strategies. The most promising treatments include outdoor activities, defocusing corrective lenses, defocusing contact lenses, orthokeratology and pharmacological treatments with low-dose atropine.
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