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Updated: Dec 11, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
What Does Influence the Neonatal Microbiome?
1Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona, 08028 Barcelona, Spain.
Insights
The human microbiome
Area of Science:
- Microbiology
- Developmental Biology
Background:
- The human microbiome's establishment and maturation are influenced by numerous pre- and post-natal factors.
- Key factors include maternal health, antibiotic exposure, delivery mode, and infant feeding practices.
Discussion:
- Investigating the precise impact and interplay of these external modulators on the microbiome is crucial.
- Understanding these dynamics can reveal new avenues for therapeutic interventions.
Key Insights:
- Early life exposures significantly shape the developing microbiome.
- The relationship between external factors and microbiome composition requires further elucidation.
Outlook:
- Significant research opportunities exist to explore microbiome modulation strategies.
- Future research should focus on harnessing these modulators for health benefits.
Abstract:
This editorial aims to provide a concise summary of the factors involved in the dynamics of microbiome establishment and maturation. At the same time, it briefly updates the current knowledge and opens new questions in this regard. Many factors act as drivers of the microbiota's development at both pre- and post-natal levels (e.g., maternal factors, antibiotic usage, type of delivery, dietary pattern, post-natal feeding type, etc.). However, it is interesting to research into its real impact, the relationship between these external modulators, and how to modulate them. The are great opportunities for new research in the field.
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