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Surface immunoglobulins on stimulated lymphocytes
The effect of phytohaemagglutinin, lipopolysaccharide, lipid A and streptococcal erythrogenic toxin on the expression of surface immunoglobulins on nerborn piglet spleen lymphocytes was studied, using iodinated anti-pig Ig, L-, mu- or gamma-antisera. It has been concluded that only IgM is the surface immunoglobulin on non-stimulated as well as LPS-stimulated piglet lymphoid cells. An increase in the numberof labelled cells was observed after cultivation of piglet spleen cells with all the mitogens tested.
The effect of phytohaemagglutinin, lipopolysaccharide, lipid A and streptococcal erythrogenic toxin on the expression of surface immunoglobulins on nerborn piglet spleen lymphocytes was studied, using iodinated anti-pig Ig, L-, mu- or gamma-antisera. It has been concluded that only IgM is the surface immunoglobulin on non-stimulated as well as LPS-stimulated piglet lymphoid cells. An increase in the numberof labelled cells was observed after cultivation of piglet spleen cells with all the mitogens tested.