[Human cells for therapeutics purpose: State of the art]
1Inserm CIC 1402, CHU de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France.
Bulletin De L'Academie Nationale De Medecine
|August 25, 2020
Abstract:
Patient-derived induced pluripotent stem cells as well as human embryonic stem cells are pluripotent and their derivation has been used for the understanding of numerous diseases. Currently they are also used for the treatment of neurologic disorders such as Parkinson disease or cardiac disorders. Gene therapy has been successful for the treatment of hemophilia A and B, hemoglobinopathies and immunodeficiencies. Hemopoietic stem cell transplantation is a well-accepted therapeutic strategy for Leukemias, whereas CAR-T cells is a new promising approach even for lymphomas and myeloma.
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